The intravenous (IV) and subcutaneous (SC) toxicity and absorption kinetics of the antileishmanial triterpene saponin PX-6518 and its active constituents maesabalide-III and -IV were studied in mice and dogs.A high-dose wash-out study of PX-6518 at 20 mg/kg SC for 5 days and a single low-dose wash-out study at 1, 2.5 or 5 mg/kg SC and IV with follo
Giant hydronephrosis is uncommon, and malignant Deck Rail End Cap hydronephrosis of unknown origin is even rarer.We report a case of a 43-year-old male patient with giant hydronephrosis without painless carnivorous hematuria.Preoperative imaging and urinary search for exfoliated Accessories - Headwear cells revealed no evidence of renal pelvic canc
Abstract Background Defensive Medicine (DM) concept refers to all medical care provided by physicians without increasing the benefits to the patient, the primary purpose of which is to prevent the risk of litigation.Although several studies have been published investigating the occurrence of DM around the world, no review conducted on DM among phys
The circadian clock regulates daily changes in behavioral, endocrine, and metabolic activities in mammals.Circadian rhythms in cellular physiology are significantly affected by aging.In particular, we previously found that aging has a profound impact on daily rhythms Square Cocktail Table in mitochondrial functions in mouse liver, leading to increa
Cet article examine la réutilisation des coquillages fossiles et décrit en même temps les anomalies ou les déformations observées sur les individus.La démarche adoptée repose en effet sur une combinaison de plusieurs activités allant de la recherche documentaire à Teething Wafers l’examen du mobilier coquillier, en passant par Deck Rail